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Those who want to boost health, muscle growth and performance are looking to enhance workouts and training with dietary options that can make them perform better- run a little faster, play basketball a little longer to build muscle more quickly. |
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Skeletal muscle is attached at two places along the bone: its origin and where it tapers down to the tendon. Thousands of cylindrical muscle fibers run from origin to tendon, and each fiber is a multi-nucleated cell. Muscle fibers are 1 to 40 microns long and 10 to 100 microns in diameter; comparatively, a strand of hair is 100 microns in diameter while a body cell is approximately 10 microns in diameter. The fibers are bound together by connective tissue that also harbors blood vessels and nerves.
Purportedly, the number of muscle fibers is fixed early in life, a similar fate mirrored by fat cells. "Theres a long-standing debate regarding ones ability to make more muscle cells versus making the existing muscle cells bigger." "Thats the hyperplasia [an abnormal increase in cells] versus hypertrophy [an enlargement in tissue not cause by cells increasing] dance. Theres evidence to support both, but I believe theres more that points to humans having a predetermined number of cells."
Because muscle fiber contains only enough ATP (adenosine triphosphate, the immediate source of cellular energy used in muscle contraction and enzymatic metabolism) to have a few muscle "twitches"- short, single contractions there are three muscle properties that keep ATP levels high for muscle building: creatine phosphate (creatine), glycolysis (sugar) and cellular respiration (oxygen). Reportedly, stores of creatine in muscle fiber are naturally 10 times more than those of ATP, allowing for muscle to subsist on relatively small reservoirs of ATP.
Skeletal muscle fibers contain 1 percent glycogen, which the muscle can break down by glycolsis into two molecules of ATP for every pair of lactic acid molecules produced. However, a build-up of lactic acid in muscles may change the pH enough to inhibit enzyme activity. Consequently, oxygen needs to be taken in to convert lactate into carbon dioxide and water.
Cellular respiration in the mitochondria helps meet ATP needs when muscle is being used during prolonged activity. It also helps the body resynthesize glycogen from lactic acid produced during glycolosis.
Many of todays performance-enhancing supplements have shown great strides in muscle performance. Whether it is antioxidants and amino acids for post-exercise repair or creatine and glutamine for muscle-building, the weekend warrior, aerobic queen or Olympian-in-training have a supplement with their name on it.
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Amino acids are know as the building blocks by which protein can be manufactured by the body. More than 300 amino acids exist, but only 20 of those make up protein.
There are many non-essential amino acids, as well, that may contribute to muscle mass. White Marsh, Md-based 4 your Health, which markets sports nutrition and other health products, reports that ornithine alpha keto-glutarate (OKG) is a potent version of the non-essential amino acid L-ornithine and may increase growth hormone. According to 4 Your Health, OKG prevents the breakdown of protein in the muscles and is a complete nutrient that can increase endurance, stamina and recovery. "Amino acids are the building blocks of our body," Delivering them alongside a highly bioavailable protein such as collagen, amino acids can help a person build lean muscle mass and shed fat."
There are also eight essential amino acids: isoleucine, leucine, lysine, methionine, phenlalanine, threonine, tryptophan and valine. They are essential because the body cannot manufacture them.
"For the most part, these eight amino acids are basically all your body needs to function correctly," wrote Vince Andrich, author of Sports Supplement Review (Mile High Publishing, 2002). He added that for optimum muscle building, three conditionally essential amino acids should also be consumed: arginine, glutamine and taurine. The body creates these compounds by itself, "but the demand for them is greatly increased after exercise, and oftentimes your body simply cannot meet this demand," Andrich wrote.
| Arginine, or L-arginine in supplement form, is synthesized from
glutamic acid and absorbed from the gastrointestinal tract. While much research has been
conducted on arginine and heart health, not as much has been done in terms of fitness. In
a 1989 study, subjects in a five-week strength-training program supplemented with 2 gms of
L-arginine and 1 gm of L-ornithine, another amino acid 2. Those taking the
arginine-ornithine combination scored significantly higher in total strength and lean body
mass compared to the placebo group. This combo also appeared to quell muscle tissue
breakdown. I would recommend these two amino acids for those looking for hardness and lean
body. Glutamine, or L-glutamine, is the most abundant amino acid found in blood and plays a large part in moving nitrogen throughout the body. Glutamine is synthesized by the enzyme L-glutamine synthetase, found in skeletal muscle. Exhaustive exercise can lower the plasma level of the amino acid, glutamine, which is an important fuel for some cells of the immune system and may have specific immunostimulatory effects. 3 During exercise, intracellular glutamine levels can drop as much as 50 percent, and plasma concentrations can dip 30 percent. Glutamine dosages range from 2,000 mg to 8,000 mg daily. I recommend glutamine to all athletics. Caution: Taking too much glutamine, which is absorbed in the intestinal tract, may lead to diarrhea in some people. Branched chain amino acids (BCAAs) are also known as stress amino acids, which are needed during times of physical stress such as exercise and weight lifting. Isoleucine, leucine and valine are active forms of BCAAs, and are absorbed from the intestinal tract. "The BCAAs have a role in the prevention of muscle loss and in the increase of muscle mass. Interestingly, in blood that was collected after an Olympic triathlon and 30-k run, those who had been supplemented with BCAAs had higher levels of glutamine and a higher immune response than the unsupplemented groups. 5 In other stressful conditions, such as during a 21 day trek at a mean altitude of 3,255 ft., BCAA supplementation (leucine, Isoleucine and Valine) helped to synthesize muscle tissue.6 Those in the placebo group experienced muscle tissue loss due to catabolism, which uses up more energy. I recommend 1,000 to 4,000 mg daily. Amino acids may well deserve the hype that surrounds them. Exercise has been linked to amino acid oxidation, which may reduce body mass if high amino acid intake is not maintains. 7 Amino acid supplementation is especially important since researchers have found that these ammonia-base compounds are prevalent in both type 1 and type 11 fibers. 8 researchers have also found that exercise additive effect on muscle protein synthesis. 9 It is important to note that essential amino acids - those not made by the body - along with carbohydrates effectively stimulate muscle-building when taken before rather than after exercise. In research conducted at Vanderbilt University Medical Center in Nashville, Tenn., researchers found the availability of energy for post-exercise muscle repair. 10 In particular, L-leucine and L-phenylalanine resulted in an increased uptake of essential amino acids. Amino acids do not always need to be taken in free form in order to experience their benefits. An alternative to taking amino acids in supplement form is taking an enzyme to help better utilize the naturally occurring amino acids in meat, eggs and other protein-rich foods. Wayne, N.J.-based Triarco Industries created Aminogen ® a patented enzyme system that releases free-form amino acids from protein containing foods. According to the company, this system has the ability to release more amino acids from protein than the digestive system alone - up to 42 percent more. According to Kathy McLeod, marketing and manager at Triarco, "Athletes need to ensure their protein intake is not being utilized by the body." |
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