- What is it and where does it come
from?
Tri-creatine malate is a compound made from
creatine monohydrate and malic
acid. The substance is so named because the compound is made from three creatine
molecules attached to one molecule of malic acid.
Tri-creatine malate is a white, odorless powder.
- What does it do and what scientific
studies give evidence to support this?
Creatine monohydrate, one of the substances that forms the compound Tri-creatine
malate, is derived from glycine, arginine and methionine and helps to produce
and circulate ATP - adenosine tri-phosphate - that is responsible for muscular
contraction.1
Regular creatine supplementation has been shown to increase total body weight2,
lean body mass3,4,5,6 muscle strength7,8 cardiovascular
ability / endurance9,10,11 brain function12 and overall
athletic performance.13,14,15,16,17,18
Not only that, but creatine monohydrate is especially effective at increasing
muscle torque and explosive strength, maintaining free testosterone levels19,
and preventing catabolism.20,21 It has also been shown to be a safe
and effective method of improving performance and body composition.22
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Malic acid is involved in the Krebs energy cycle as an intermediate
substance, and helps to provide energy to the body. When malic acid and creatine
monohydrate form the compound Tri-creatine malate, the resulting product is more
water-soluble than regular creatine monohydrate, eliminates the possibility of
gastric disruption, and is more efficient at efficaciously impacting the ATP
cycle. Furthermore, Tri-creatine malate is believed to offer greater
bioavailability over regular creatine monohydrate.
Creatine Malate aid in a faster and more efficient transport of creatine into
the muscle cells. Due to its dissolvability, Creatine yields significant
strength and lean mass increases with no upset stomach, cramping, water
retention or loading stage.
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Users of Tri-creatine malate report substantial increases in endurance and
recovery from intense exercise of appropriate duration.
No physiological need for Tri-creatine malate exists and thus no symptoms of
deficiency exist.
Athletes and bodybuilders can benefit from Tri-creatine malate
supplementation. Women and men from all age populations can derive benefit from
Tri-creatine supplementation because of Tri-creatines ability to enhance quality
of life as a result of its effects as listed above.
Strictly adhere to label recommendations.
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- REFERENCES
- 1. Kleiner, S.M. and M. Greenwood-Robinson. 1998. Power
Eating. Champaign, Illinois: Human Kinetics.
- 2. Kutz MR, Gunter MJ. Creatine monohydrate supplementation on body weight
and percent body fat. J Strength Cond Res. 2003 Nov;17(4):817-21.
- 3. Racette SB. Creatine supplementation and athletic performance. J Orthop
Sports Phys Ther. 2003 Oct;33(10):615-21.
- 4. Kreider, R.B., 1999. Dietary supplements and the promotion of muscle
growth with resistance exercise. Sports Medicine 27:97-110.
- 5. Becque, M.D., et al. 2000. Effects of oral creatine supplementation on
muscular strength and body composition. Medicine and Science in Sports and
Exercise 32: 654-658.
- 6. Ingwal JS, Weiner CD, Morales MF, Davis E, Stockdale FE: Specificity of
creatine in the control of muscle protein synthesis. J Cell Biol 63:145-151,
1974.
- 7. . Rawson ES, Volek JS. Effects of creatine supplementation and resistance
training on muscle strength and weightlifting performance. J Strength Cond Res.
2003 Nov;17(4):822-31.
- 8. Kambis KW, Pizzedaz SK. Short-term creatine supplementation improves
maximum quadriceps contraction in women. Int J Sport Nutr Exerc Metab. 2003
Mar;13(1):87-96.
- 9. Chwalbinska-Moneta J. Effect of creatine supplementation on aerobic
performance and anaerobic capacity in elite rowers in the course of endurance
training. Int J Sport Nutr Exerc Metab. 2003 Jun;13(2):173-83.
- 10. Rico-Sanz, J. et al. (2000). Creatine enhances oxygen uptake and
performance during alternating intensity exercise. Medicine and Science in
Sports and Exercise. 32: 379-385.
- 11. Urbanski, R.L., et al. 1999. Creatine supplementation differentially
affects maximal isometric strength and time to fatigue in large and small muscle
groups. International Journal of Sport Nutrition 9: 136-145.
- 12. Rae C, Digney AL, McEwan SR, Bates TC. Oral creatine monohydrate
supplementation improves brain performance: a double-blind, placebo-controlled,
cross-over trial. Proc R Soc Lond B Biol Sci. 2003 Oct 22;270(1529):2147-50.
- 13. Lehmkuhl M, Malone M, Justice B, Trone G, Pistilli E, Vinci D, Haff EE,
Kilgore JL, Haff GG. The effects of 8 weeks of creatine monohydrate and
glutamine supplementation on body composition and performance measures. J
Strength Cond Res. 2003 Aug;17(3):425-38.
- 14. Kurosawa Y, Hamaoka T, Katsumura T, Kuwamori M, Kimura N, Sako T, Chance
B. Creatine supplementation enhances anaerobic ATP synthesis during a single 10
sec maximal handgrip exercise. Mol Cell Biochem. 2003 Feb;244(1-2):105-12.
- 15. Gill ND, Hall RD, Blazevich AJ. Creatine serum is not as effective as
creatine powder for improving cycle sprint performance in competitive male
team-sport athletes. J Strength Cond Res. 2004 May;18(2):272-5.
- 16. Rawson, E.S., et al. 1999. Effects of 30 days of creatine ingestion in
older men. European Journal of Applied Physiology 80: 139-144.
- 17. Jones, A.M., et al. 1999. Oral creatine supplementation improves multiple
sprint performance in elite ice-hockey players. Journal of Sports Medicine and
Physical fitness 39:189-196.
- 18. Skare OC, Skadberg, Wisnes AR: Creatine supplementation improves sprint
performance in male sprinters. Scand J Med Sci Sports 11:96-102, 2001.
- 19. French DN, Volek JS, Ratamess NA, Mazzetti SA, Rubin MR, Gomez AL,
Wickham RB, Doan BK, McGuigan MR, Scheett TP, Newton RU, Dorofeyeva E, Kraemer
WJ: The effects of creatine supplementation on resting serum hormonal
concenrtrations during short-term resistence training overreaching. Med Sci
Sports & Exerc 33:S203, 2001.
- 20. Persky AM, Brazeau GA. Clinical pharmacology of the dietary supplement
creatine monohydrate. Pharmacol Rev 2001 Jun;53(2):161-76
- 21. Parise G, Mihic S, MacLennan D, Yarasheski KE, Tarnopolsky MA. Effects of
acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle
protein synthesis. J Appl Physiol 2001 Sep;91(3):1041-7
- 22. Robinson TM, Sewell DA, Casey A, Steenge G, Greenhaff PL. Dietary
creatine supplementation does not affect some haematological indices, or indices
of muscle damage and hepatic and renal function. Br J Sports Med 2000
Aug;34(4):284-8
