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Guide for MSM
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MSM is a naturally occurring, organic source of dietary sulfur, the mineral that plays a crucial role in forming muscles, nails, hair, and skin as well as in other bodily functions. Dr. Stanley Jacob of the Oregon Health Sciences University Medical School in Portland has been the lead researcher and developer of refined MSM supplements, a product that he derived from another naturally occurring compound, dimethyl sulfoxide (DMSO). MSM is chemically very similar to DMSO and is also referred to as DMSO2 and dimethyl sulfone. Like DMSO, MSM is a versatile biochemical agent within the body. MSM is becoming an increasingly popular supplement mainly to reduce allergic reactions to pollen and foods and to relieve the pain and inflammation of arthritis, sprains, tendinitis, and similar conditions.
 
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Benefits and uses
MSM has various potential therapeutic applications that go beyond its ability to relieve allergies and soothe sore muscles and joints. Many people use it to flush toxins from the body. Others are taking it to help treat chronic fatigue, psoriasis, acne, constipation, and gastrointestinal ailments. MSM acts much like an antacid to control over-acidity in the stomach. Some studies suggest that it may be able to play a part in treating such serious conditions as lupus, breast cancer, and diabetes. MSM  levels in the body are thought to decline with age.
 
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Do scientists know how it works?
Nutritionists recognize the sulfur in MSM as a crucial nutrient for building healthy cells, forming collagen and other bodily tissues, and producing certain enzymes, vitamins, and amino acids. Sulfur is an important component of the hormone insulin, which helps to regulate carbohydrate metabolism and balance blood sugar levels. MSM may help reduce allergic reactions by blocking allergens or competing with them for mucous membrane receptor sites. MSM may also increase the body's natural immune response and act as an antioxidant. Tests have shown that MSM   is active against Giardia lamblia and other parasites.
 
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Recent findings
Few studies in recent years have focused on the effects of MSM intake.
In 1991 Russian researchers found that prolonged oral administration of DMSO and MSM lessen the destructive changes in the joints of mice with arthritis.
Five years earlier researchers had shown that DMSO and MSM could protect mice from autoimmune disease and thereby significantly extend the animals' average life span.
Recent investigations have been more specialized, such as a 1998 study that measured the blood concentrations of DMSO and MSM in patients receiving bone marrow transplants, since DMSO is used to preserve stem cells.
 
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Food sources
MSM is found in small amounts in various foods, especially raw, fresh fruits and vegetables and in dairy foods. Seafood and meats lose their MSM in cooking; MSM is also diminished in processed foods. Green food supplements such as algae may contain some MSM.

 
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MSM for the Skin

 Topically MSM may improve the integrity and resilience of the skin and collagen tissue, and the building of Healthy Skin Cells while promoting protective antioxidant activity.

Product  Recommendations

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Liquid Glucosamine Formula - Pain Relief - Anti-Inflammatory   - High Absorption Rate - Lemon Lime.  1 oz. contains: Glucosamine Sulfate. 500 mg, Chondroitin Sulfate. 400 mg. MSM  500 mg 36 Servings

MSM 1000 mg. 
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Hair and Skin provides nutrients necessary for healthy hair, skin and nails. It includes effective doses of MSM (MethylSulfonylMethane), a sulphur source that provides necessary nutrients for the building process of proteins in Hair and Skin. Glucosamine, which aids in collagen and connective tissue formation. Concentrated Enzymes, that help with the proper break down of food allowing delivery of sufficient nutrients to the extremities. Biotin, essential ingredient for formation of hair, skin and nails, and a blend of other traditional herbs such as Horsetail, Rosemary, and Nettle More info on Glucosmine Buy Hair and Skin Nutrients

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MSM Liposome Cream to support the cellular structure of the healthy skin. Ultra-hydrating Lecithin and Grape oil are precisely blended to deliver the essential fatty acids your skin needs for maximum resistance to the elements. 

Hair, Skin and Nail Formula with MSM! Plus Colloidal Silica for Maximum Benefits, with Horsetail. Buy Hair and Skin

bulletTypes of products
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MSM comes in 500 to 1,000 mg capsules and tablets, as well as a powder and Skin Care Products Some producers combine it with other nutrients such as chondroitin, glucosamine sulfate, and vitamin C.
 
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Safety
MSM seems to be remarkably safe. Toxic effects have not been shown even in doses many times higher than average. Some people experience minor side effects such as diarrhea, headache, and fatigue. MSM does not cause the bad breath associated with taking or using DMSO.
 
References
Egorin, M.J., et al., " Plasma concentrations and pharmacokinetics of dimethylsulfoxide and its metabolites in patients undergoing peripheral-blood stem-cell transplants," J Clin Oncol (1998), 16(2):610-15
Morton, J.I., and B.V. Siegel, "Effects of oral dimethyl sulfoxide and dimethyl sulfone on murine autoimmune lymphoproliferative disease," Proc Soc Exp Biol Med (1986), 183(2):227-30
Muravev, I.V., et al., "[Effect of dimethyl sulfoxide and dimethyl sulfone on a destructive process in the joints of mice with spontaneous arthritis[," Patol Fiziol Eksp Ter (1991), (2):37-39
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