Research indicates that LEM helps decrease chronic
hepatitis B infectivity, as measured by specific liver and blood markers. A highly
purified intravenous form of lentinan has been employed in Japan for the treatment of
recurrent stomach cancer, which increases survival with this cancer (particularly when
used in combination with chemotherapy). These effects may be due to shiitake’s
ability to stimulate specific types of white blood cells called T-lymphocytes. Case
reports from Japan are also highly suggestive that lentinan is helpful in treating
individuals with HIV infection. However,
large-scale clinical trials have not yet been performed confirming this action.2
How much should I take?
The traditional intake of the whole, dried shiitake mushroom, in soups or as a
decoction, is 6-16 grams per day. For LEM, the intake is 1-3 grams two to three times per
day until the condition being treated improves. As LEM is the more concentrated and hence
more potent extract, it is preferred over the crude mushroom. Tincture, in the amount of
2-4 ml per day, can also be used.
Are there any side effects
or interactions? Shiitake has an excellent record of safety but has been known
to induce temporary diarrhea and abdominal bloating when used in high dosages. Its safety
during pregnancy has not yet been established.
- References:
- 1. Jones K. Shiitake: The Healing Mushroom.
Rochester, VT: Healing Arts Press, 1995.
2. Hobbs C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 125-8.
