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Caffeine (Caffedrine®, NoDoz®, Quick Pep®, Vivarin®)
Caffeine/Aspirin (Anacin® and Others)
On This Page
Interactions with Herbs
Interactions with Foods and Other Compounds

Caffeine is a central nervous system stimulant drug used as an aid to stay awake, for mental alertness due to fatigue, and as an adjunct with other drugs for pain relief. Caffeine is available alone as a nonprescription drug (Caffedrine®, NoDoz®, Quick Pep®, Vivarin®). It is also available in combination with other nonprescription drugs (caffeine/aspirin, Anacin® and others) and in prescription drug combinations for relief of pain and headache.
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Interactions with Dietary Supplements

Calcium
In 205 healthy postmenopausal women, caffeine consumption (three cups of coffee per day) was associated with bone loss in women with calcium intake of less than 800 mg per day.1 In a group of 980 postmenopausal women, lifetime caffeine intake equal to two cups of coffee per day was associated with decreased bone density in those who did not drink at least one glass of milk daily during most of their life.2 However, in 138 healthy postmenopausal women, long-term dietary caffeine (coffee) intake was not associated with bone density.3 Until more is known, postmenopausal women should limit caffeine consumption and consume a total of approximately 1,500 mg of calcium per day (from diet and supplements).
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Interactions with Herbs
Guaraná (Paullinia cupana)
Guaraná is a plant with a high caffeine content. Combining caffeine drug products and guaraná increases caffeine-induced side effects.
 
Ephedra sinica (Ma huang) click here for Ephedra products
Many herbal weight loss and quick energy products combine caffeine or caffeine-containing herbs with ma huang (Ephedra sinica). This combination may lead to dangerously increased heart rate and blood pressure and should be avoided by people with heart conditions, hypertension, diabetes, or thyroid disease.4

Product Recommendations
Mega-Pro

Caffeine
Helps restore mental alertness or wakefulness when experiencing fatigue or drowsiness.
Each tablet contains:
Caffeine Anhydrous...200 mg
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Mega-Pro
Vasopro

With 25 mg. Ephedrine HCI and 200 mg. More info on Ephedrine Buy Vasopro
 
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Interactions with Foods and Other Compounds
Food
Caffeine is found in coffee, tea, soft drinks, and chocolate. To reduce side effects, people taking caffeine-containing drug products should limit their intake of caffeine-containing foods/beverages.
Tobacco
Smoking can increase caffeine metabolism,5 decreasing effectiveness. Smokers who use caffeine-containing drug products may require higher doses of caffeine to achieve effectiveness.
Natural Energy Supplements
Ask the Expert Energy Supplements (click)
Also see the following articles: Thermo, Dyhydration , Water
 
References:
1. Harris SS, Dawson-Hughes B. Caffeine and bone loss in healthy postmenopausal women. Am J Clin Nutr 1994;60:573–78.
2. Barrett-Connor E, Chang JC, Edelstein SL. Coffee-associated osteoporosis offset by daily milk consumption. The Rancho Bernardo Study. JAMA 1994;271:280–83.
3. Lloyd T, Rollings N, Eggli DF, et al. Dietary caffeine intake and bone status of postmenopausal women. Am J Clin Nutr 1997;65:1826–30.
4. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, Pharmaceutical Press, 1994, 88–89.
5. Joeres R, Klinker H, Heusler H, et al. Influence of smoking on caffeine elimination in healthy volunteers and in patients with alcoholic liver cirrhosis. Hepatology 1988;8:575–79.
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