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With names like devil's tongue and voodoo lily, it must have been difficult for a plant tuber to make it past 19th century priests and missionaries in Asia and remain on the plates of the average Japanese citizen. Yet thankfully, it did. For over 2,000 years, devil's tongue (Amorphophallus konjac) has been cultivated in Asia for its nutritious tuber. The plant's popular names no doubt derive from its distinctive appearance. Reaching heights upwards of five feet, it contains a giant flower that consists of a stiff, protruding, fiery-red spike that juts out of a purplish-red spathe. The spathe—the wrap-around petal distinctive of lilies—is often more than a foot high. The spike is what looks like a devil's tongue—it shoots up out of the spathe, rising as much as two or three times taller, and twists slightly.

On This Page
Of Devil's Tongue, Cacti, and Crabs
Oh, What a Little Fiber Can Do!
Glucomannan on Trial
Safety
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The tubers have traditionally been pounded to yield a powder for making noodles or gelatin for adding to stews, sauces, and soups. The tuber renders these foods richer, thicker, and more satisfying in much the same way that white flour or corn starch improves the texture of similar foods in the United States. But the Japanese have a better thing going than we do with our white starches. Ours tend to constipate, and are full of "empty" calories that contribute to weight gain and obesity. In comparison, konjac, or konnyaku, as it's called today, contains beta carotene, thiamin, and a number of minerals, including magnesium and manganese. It also contains chromium, a mineral with potential benefits in controlling sugar cravings and treating diabetes. But these are not the most impressive of konjac's ingredients: Glucomannan raises this tuber to near-angelic status.

Despite its evil-sounding nicknames, konjac has long been believed by the Japanese to move toxins out of the digestive tract. Studies show that they are probably right, and that konjac may help to prevent many diseases, including cancer, diabetes, gallstones, obesity, and heart disease. These studies provide support for food manufacturers who propose replacing white flour with konjac powder, not just to clean the intestines, but to serve as a weight-loss ingredient in many common foods.

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Oh, What a Little Fiber Can Do!
Glucomannan is already available as a dietary supplement. Asian women have claimed for years that it helps them maintain a desired weight, and more and more Americans are determined to find out if it's true. Glucomannan is a polysaccharide, which means that chemically it is made up of simple sugars—specifically, mannose and glucose. It is also a soluble fiber and can absorb up to 200 times its weight in water.

Glucomannan reduces blood fats, discourages weight gain, helps to keep blood sugar levels normal, and relieves constipation. When ingested, it takes on a jelly-like consistency and expands to make the stomach feel full. People are therefore sated more quickly and are less likely to overeat, according to results of trials in which obese patients were put on calorie-restricted diets and glucomannan. In addition, like most food fiber, glucomannan acts as a bulking agent in the colon, which stimulates peristalsis (the muscular movement that causes bowel evacuation).

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Glucomannan on Trial
Clinical studies confirm that glucomannan in konjac tubers lowers cholesterol—both total cholesterol and low-density lipoprotein (LDL) cholesterol—without affecting diastolic blood pressure.

When given to obese children, konjac glucomannan (KG) decreased  cholesterol and triglyceride levels significantly, without any negative effects. Obese adults who took 1 gram KG with 8 ounces of water one hour before meals three times a day for eight weeks reported an average weight loss of 5.5 pounds, and overall reductions in total cholesterol and LDL cholesterol levels.

In one double-blind trial, ten days of treatment with KG returned the bowel habits of patients with chronic constipation to normal. Another study showed that patients given either 3 or 4 grams daily noted an average increase of three and six more bowel movements per week, respectively, without additional diarrhea or flatulence.

Konjac glucomannan helped to keep glucose at optimal levels in baboon blood, suggesting that KG may help control glucose levels in diabetics. A recent study indicates that this is likely to be true: When used along with conventional treatment, KG not only helped normalize and maintain blood sugar levels in patients with type 2 diabetes, it also lowered both cholesterol and systolic blood pressure.

Experimental studies also indicate that KG may protect against certain types of cancer. For those of us over the age of 60, this is welcome news. When elderly people are given glucomannan, the bacteria in the gut changes and encourages the growth of the so-called "good bacteria" such as Bifidobacterium. Increases in good bacteria are associated with a reduction in pro-cancerous nitrosamines, proteins thought to be responsible for the development of liver cancer and other cancers. Good bacteria also encourage better gut motility—motion, including peristalsis that leads to a bowel movement — thereby helping to move waste products out of the body before they can promote cancer or other illnesses.

Studies on diabetic rats indicate that long-term supplementation with konjac glucomannan may help prevent heart attacks and strokes in people who have diabetes. In diabetic rats put on diets high in cholesterol, glucomannan prevented the formation of aortal plaques, deposits that increase heart disease risk. Glucomannan may do this in humans, too, by reducing LDL cholesterol and blood sugar levels.

 
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Safety
People who want to use konjac glucomannan supplements to enhance weight loss or manage cholesterol should keep tabs on their nutrient status. An early study on diabetic and healthy individuals found that KG reduced the absorption of vitamin E, an action that is likely due to enhanced bile activity, which speeds the evacuation of fats—as well as the vitamins that use fats for absorption and utilization—from the body. In studies with rats, KG increased fecal bile acid output, an action directly attributed to KG's cholesterol-reducing effects. Don't be alarmed, though. It's not unusual for supplements that alter blood lipid status to have an effect on fat-soluble vitamins. Ask your doctor how to plan your meals and multivitamin supplements around KG so that you get proper nutrition.

KG changed the availability of calcium, zinc, iron, and copper in rats, but these elements were not changed during human trials and are not considered a source of concern.

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Of Devil's Tongue, Cacti, and Crabs
Although konjac is not the only plant source of glucomannan (aloe, for example, also contains this fiber), it is the most accessible source. Konjac has long been used in Asia for culinary purposes, and is readily available, processed into powder. Other plant sources containing additional ingredients may not be as pure in glucomannan content as konjac tubers are. For example, aloin is the cathartic anthraquinone laxative that causes bitter aloe—the medicinal preparation of aloe that is used for constipation, not burns—to trigger painful intestinal cramping. Konjac and konjac glucomannan don't contain aloin, and don't have this uncomfortable effect.

Chitosan and chitin are two other polysaccharides used in weight-loss products. These fibers slow the transit time of food as it moves through the digestive system, preventing dietary fat and cholesterol from adding pounds to the waist or fat to the bloodstream. Chitin is obtained from shellfish and is similar in chemical structure to cellulose and starch. It's heated with a chemical solution to make Chitosan.

Both are indigestible and speed food through the digestive process. Reports that they cleanse the colon, regulate bowel habits, and reduce blood pressure and tumors are the result of an estimated 1,000 studies. These products come from marine animals, however, rather than plants.

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References

Walsh D, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984; 8(4): 289-293.
Vorster H and Dejager J. The effect of the long-term ingestion of konjac-glucomannan on glucose tolerance and immunoreactive insulin values of baboons. S Afr Med J 1984 65 (20): 805-808.
Arville A and Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 1995 61(3): 585-9
Doi K, Matsuura M, Kawara A, Tanaka T, Baba S. Influence of dietary fiber (konjac mannan) on absorption of vitamin B12 and vitamin E. Tohoku J Exp Med 1983; 141 Suppl: 677-81.
Liviere C, Novzi F, Lorini R. Pediatr Med Chir 1992 14(2): 195-8.
Vuksan V, Jenkins D, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetics. A randomized controlled metabolic trial. Diabetes Care 1999; 22 (6): 913-9.
Marzio L, Del Biano R, Donne M, et al. Mouth-to-cecum transit time in patients affected by chronic constipation: effect of glucomannan. Am J Gastroenterol 1989; 84(8): 881-91.
Mitsuoka T. The effect of nutrition on intestinal flora. Nahrung 1984; 28 (6-7): 619-25.
Marsicano LJ. Use of glucomannan dietary fiber in changes in intestinal habit. GEN 1995 49(1): 7-14.
Hozumi T. Long-term effects of dietary fiber supplementation on serum glucose and lipoprotein levels in diabetic rats fed a high cholesterol diet. Endocr J 1995; 42(2): 187-92.
Cairella M. Evaluation of the action of glucomannan on metabolic parameters and on the sensation of satiation in overweight and obese patients. Clin Ter. 1995 146(4): 269-74.
Rosado JL. Physico-chemical properties related to gastrointestinal function of 6 sources of dietary fiber. Rev Invest Clin 1995 47 (4): 283-9.
Duke J and Stephen M. Beckstrom-Sternberg. Phytochemical Database, USDA-ARS-NGRL, Beltsville Agricultural Research Center, Beltsville Maryland.
Hou Y, Zhang L, Zhou H, et al. Influences of refined konjac meal on the levels of tissue lipids and the absorption of four minerals in rats. Biomed Environ Sci 1990; 3(3): 306-14.
Wu J and Peng S. Comparison of hypolipidemic effect of refined konjac meal with several common dietary fibers and their mechanisms of action. Biomed Environ Sci 1997; 10(1): 27-37.
Jing, S.B., et al., "Effect of chitosan on renal function in patients with chronic renal failure," J Pharm Pharmacol (1997), 49(7):721-23.
Xue, C., et al., "Antioxidative activities of several marine polysaccharides evaluated in a phosphatidylcholine-liposomal suspension and organic solvents," Biosci Biotechnol Biochem (1998), 62(2):206-09.
Drenda, P., et al., "[Evaluation of the usefulness of dressings made from chitosan and lyophilized human placenta on wound healing]," Wiad Lek (1997), 50 Su 1 Pt 2:252-56.
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