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Hypoglycemia

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The technical meaning of hypoglycemia is low blood sugar. Occasionally, hypoglycemia can be a potentially dangerous problem (for example, when caused by a tumor of the pancreas, liver disease, or from injecting too much insulin).

More often, however, when people say they have hypoglycemia, they are describing a group of symptoms that occur when the body reacts to increasing blood sugar levels after eating and may overdo its efforts to bring blood sugar back down. Common symptoms are fatigue, anxiety, headaches, difficulty concentrating, sweaty palms, shakiness, excessive hunger, drowsiness, abdominal pain, and depression. This condition is sometimes called reactive hypoglycemia.

On This Page
Dietary changes that may be helpful
Any side effects
Nutritional supplements that may be helpful
Many people with reactive hypoglycemia do not literally have low blood sugar levels,1 and many people who do have low blood sugar levels do not have any symptoms of reactive hypoglycemia.2 Some evidence suggests that reactive hypoglycemia may partially be a psychological condition.3 As a result of this confusion, some medical doctors have decided that reactive hypoglycemia essentially does not exist.4

Nonetheless, when they are monitored continuously, people with reactive hypoglycemia have been found to have large surges in blood levels of the hormone epinephrine at the moment they suffer their symptoms.5

Dietary changes that may be helpful: Doctors of natural medicine generally find that individuals with hypoglycemia usually improve when they eliminate refined sugars, caffeine, and alcohol from their diet; eat foods high in fiber (such as whole grains, fruits, vegetables, legumes, and nuts); and eat small, frequent meals. Few studies have investigated the effects of these changes, but the meager amount of research is generally supportive.6 7 8 9 Some symptoms of low blood sugar may be related to or made worse by food allergies.10

Some people claim to have fewer symptoms when eating a high-protein, low-carbohydrate diet. However, research shows that increasing protein intake can actually impair the body’s ability to process sugar,11 probably because protein increases insulin levels12 (insulin reduces blood sugar levels). Despite these facts, on the basis of anecdotes from patients, some nutritionally oriented doctors continue to try high-protein diets when the usual high-fiber/high-carbohydrate diets do not seem to reduce symptoms.

Nutritional supplements that may be helpful: Research has shown that supplementing with chromium (200 mcg per day)13 or magnesium (340 mg per day)14 can prevent blood sugar levels from falling excessively in people with hypoglycemia.Ayurvedic helps sugar levels. Niacinamide (vitamin B3) has also been found to be helpful for hypoglycemic individuals.15 Other nutrients, including vitamin C, vitamin E, zinc, copper, manganese, and vitamin B6, help control blood sugar levels in diabetics.16 Since the body regulates high and low blood sugar in similar ways, these nutrients might be helpful for hypoglycemia as well.

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    References:
    1. Palardy J, Havrankova J, Lepage R, et al. Blood glucose measurements during symptomatic episodes in patients with suspected postprandial hypoglycemia. N Engl J Med 1989;321:1421–25.
    2. Kwentus, JA, Achilles JT, Goyer PF. Hypoglycemia etiologic and psychosomatic aspects of diagnosis. Postgrad Med 1982;71(6):99–104.
    3. Johnson DD, Dorr KE, Swenson WM, Service J. Reactive hypoglycemia. JAMA 1980;243:1151–55.
    4. Yager J, Young RT. A non-editorial on non-hypoglycemia. N Engl J Med 1974;291:905–8.
    5. Chalew, SA, McLaughlin JV, Mersey JH, et al. The use of the plasma epinephrine response in the diagnosis of idiopathic postprandial syndrome. JAMA 1984;251(5):612–15.
    6. Sanders LR, Hofeldt FD, Kirk MC, Levin J. Refined carbohydrate as a contributing factor in reactive hypoglycemia. Southern Med J 1982;75(9):1072–75.
    7. Permutt MA. Postprandial hypoglycemia. Diabetes 1976;25: 719–33.
    8. O’Keefe SJD, Marks V. Lunchtime gin and tonic as a cause of reactive hypoglycemia. Lancet 1977;i:1286–88.
    9. Hofeldt FD. Reactive hypoglycemia. Metabol 1975;24(10):1193–208.
    10. Rippere V. A little something between meals: masked addiction not low blood blood-sugar. Lancet 1979(June 23):1349 [letter].
    11. Anderson JW, Herman RH. Effects of carbohydrate restriction on glucose tolerance of normal men and reactive hypoglycemic patients. Am J Clin Nutr 1975;28:748.
    12. Ullrich IH, Peters PJ, Albrink JA. Effect of low-carbohydrate diets high in either fat or protein on thyroid function, plasma insulin, glucose, and triglycerides in healthy young adults. J Am Coll Nutr 1985;4:451.
    13. Anderson RA et al. Chromium supplementation of humans with hypoglycemia. Fed Proc 1984;43:471.
    14. Stebbing JB et al. Reactive hypoglycemia and magnesium. Mag Bull 1982;2:131–34.
    15. Shansky A. Vitamin B3 in the alleviation of hypoglycemia. Drug Cosm Ind 1981;129(4):68–69,104–5.
    16. Gaby AR, Wright JV. Nutritional regulation of blood glucose. J Advancement Med 1991;4(1):57–71.
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