Suprabiotic 150 caps by Neobium
- Brand: Neobium
- Product Code: 606989963833
- Availability: 6
- Was $56.99Now
Slimming Probiotic for Metabolism Health
What if I told you that your gut was the most important endocrine organ in your body, controlling everything from metabolism to body composition to your health and mood?
What if I told you that it was governed by trillions of bacteria, called the “microbiota”, who have long ago invaded and colonized it? What if I told you that this is as bad as it sounds? They are not all friendly – there is a war going on inside your body — and, the bad guys are winning!
Beyond the cutting edge of probiotic research and development, SupraBiotic combines 6 probiotic strains, 100 billion colony forming units, with an unrivalled auxillary formula, optimized to turn the bacterial milieu of your gut into a mean, lean body machine. It does not stop at fat loss, though, fighting and fixing inflammatory pathways that wreak havoc on insulin sensitivity, cardiovascular and digestive health, the immune system, and even your skin.
The most well-known, commercial probiotics are Lactobacillus and Bifidobacterium. They are also among the most common in the body, along with several other really interesting ones which are not commercially available, but we can manipulate with supplementation as you will soon learn.
Unfortunately, Lactobacillus belong to the Firmicutes phylum which is associated with weight gain and obesity. Just a 20% increase in Firmicutes with an equal decrease in Bacteroides results in an increased energy harvest of 150 calories per day in humans. That is equal to 15lbs of fat per year! Modern food processing and the Western style diet promote these negative changes in microbial proportions. Thus, one can plainly see why it can be so difficult to get lean, as well as how easily obesity has become an epidemic. In addition, probiotic treatment with several Lactobacillus species are directly associated with weight gain, body mass index, obesity, and Type-2 diabetes. They don’t tell you that on the label.
You may have noticed that almost no probiotic formulas contain just a single species of bacteria, nowadays. And, if you did not, I will just say that it is for a good reason. They work better in combination. Microbial diversity is good. Essentially, a diverse gut is a healthy gut. However, you do not want to just throw every single commercially available species and strain into a product as so many companies do. They need to be rationally combined. If not, they can interfere with each other’s actions and compete for space and resources. But, the most interesting benefit of probiotic combinations is through cross-feeding. This is when one bacterial strain produces metabolites the others use for fuel, as we will discuss in a bit. Right now, let’s get to the SupraBiotic™ probiotic combination.
Suppresses the accumulation of body weight and fat mass Improves lipid metabolism and insulin/leptin sensitivity Combats LPS induced inflammation and leaky gut Inhibits enemy of leptin/insulin sensitivity Toll-like Receptor-4 (TLR-4) activity. Reinforces intestinal epithelial cells and mucosa, improving the physical barrier of the intestine.
Bifidobacterium animalis subsp. lactis
Increases short chain fatty acid (SCFA) production to distal parts of the colon, meaning it has a long acting mechanism of action. Shifts the microbiota toward that of a lean phenotype
Negatively associated with body mass index and obesity. Reduces hunger, weight gain, fat mass accumulation and preserves glucose tolerance. Reverses inflammation induced insulin resistance. Improved the efficacy of AMPK agonist metformin, suggesting potentiation with this pathway. Reduces LPS and inflammation, preserving gut barrier function and recovery in response to stress.
Higher in lean subjects. Inhibits weight gain, fat storage, fat cell formation, adipose cell size, and adipose tissue mass. Reduces plasma glucose, insulin, triglycerides, and oxidative stress levels. Increases fatty acid oxidation. Improves insulin and leptin sensitivity against an obesity promoting diet via up-regulation of PPAR-alpha. Increases in leptin levels even during weight loss. Preferentially directs calories toward lean tissue. Synergistic with other probiotics as well as with polyphenols. Increases levels of the genus Bacteroides while reducing the Firmicutes:Bacteroides ratio. Potent anti-inflammatory, attenuating signaling of LPS and TLR-4. Increased tight junction protein formation and improved intestinal barrier function.
Mitigates bodyweight and fat mass increases in obesity promoting diets. Decreases both visceral and subcutaneous adipose tissue. Increases insulin and leptin sensitivity via adiponectin (which activates AMPK). Elevates total energy expenditure. Increases tight-junction protein expression and improves intestinal barrier function. Inhibits LPS production, intestinal permeability, and adipose tissue inflammation.
Reduces weight gain, fat mass, and fat synthesis. Increases Bacteroides and improves the obesity associated Firmicutes:Bacteroides ratio. Increases insulin and leptin sensitizing peptide adiponectin (which activates AMPK). Raises leptin levels even with weight loss. Enhances fatty acid oxidation and insulin sensitivity via activation of AMPK in both adipose and skeletal muscle tissue.
Decreases LPS and LPS induced systemic inflammatory markers, as well as TLR-4 expression. Protective of microbial composition, inflammation, tight junction proteins, and gut barrier function against a high fructose diet as well as alcohol. Anxiolytic in response to stress.
Higher in lean than obese populations and levels predict leanness, in general. Reduces bodyweight, visceral adipose tissue, and fat mass, while improving insulin resistance.
Synergistic with polyphenols
Most important as THE archetypal cross-feeder of several of the most important and impressive strains of bacteria. Produces acetate and oligosaccharides which are then consumed by acetate utilizing, butyrate and propionate producing bacteria — the ones that are not commercially available.